Disease: Mental deficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WDR62 O43379 WD repeat domain 62 2.4E-23 0.597 0.615
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846
SYNGAP1 Q96PV0 synaptic Ras GTPase activating protein 1 Enzyme modulator 1.00 0.584 0.577
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
SIN3A Q96ST3 SIN3 transcription regulator family member A Enzyme 1.00 0.551 0.692
SHANK3 Q9BYB0 SH3 and multiple ankyrin repeat domains 3 1.00 0.550 0.731
SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains 2 8.4E-07 0.663 0.385
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
RAI1 Q7Z5J4 retinoic acid induced 1 Transcription factor 1.00 0.545 0.731
RAB39B Q96DA2 RAB39B, member RAS oncogene family 0.83 0.619 0.615
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTCHD1 Q96NR3 patched domain containing 1 Receptor 0.98 0.678 0.385
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
PAX6 P26367 paired box 6 1.00 0.450 0.769
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit Enzyme 1.00 0.700 0.423
MEF2C Q06413 myocyte enhancer factor 2C Transcription factor 1.7E-02 0.517 0.769
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MCPH1 Q8NEM0 microcephalin 1 Nucleic acid binding 7.8E-30 0.540 0.846
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769